Queen of Castile and León, Queen consort of Aragon, Majorca, Naples, Sicily and Valencia Isabella van Castilië, Aragon
1451 - 1504 (53 years)
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| Queen of England Catherine d'Aragon 1485-1536 |
| Queen of England Catherine d'Aragon | |
| B: | 15 Dec 1485 |
| Alcalá de Henares, Madrid, Madrid, Spain | |
| D: | 7 Jan 1536 |
| Huntingdonshire, England | |
 | Arthur Tudor 1486-1502 |
| Arthur Tudor | |
| B: | 20 Sep 1486 |
| Winchester, Hampshire, England | |
| M: | 14 Nov 1501 |
| London, England | |
| D: | 2 Apr 1502 |
| (infant son) Tudor 1513-1513 |
| (infant son) Tudor | |
| B: | Oct 1513 |
| D: | Oct 1513 |
| (infant daughter) Tudor, (2nd) 1518-1518 |
| (infant daughter) Tudor, (2nd) | |
| B: | 10 Nov 1518 |
| D: | 16 Nov 1518 |
| Duke of Richmond Henry FitzRoy 1519-1536 |
| Duke of Richmond Henry FitzRoy | |
| B: | Jun 1519 |
| Blackmore, Essex, England | |
| D: | 22 Jul 1536 |
| St James, Dorset, England | |
| Duke of Cornwall Henry Tudor, II 1514-1514 |
| Duke of Cornwall Henry Tudor, II | |
| B: | Dec 1514 |
| D: | Dec 1514 |
| Duke of Cornwall Henry Tudor, I 1511-1511 |
| Duke of Cornwall Henry Tudor, I | |
| B: | 1 Jan 1511 |
| Richmond, Surrey, England | |
| D: | 22 Feb 1511 |
| Richmond, Surrey, England | |
| Queen of England and Ireland Mary Tudor, I | |
| B: | 18 Feb 1516 |
| Greenwich, Kent, England | |
| D: | 17 Nov 1558 |
| St James Westminster, London, England | |
| King of Spain Philip Hapsburg, II 1527-1598 |
| King of Spain Philip Hapsburg, II | |
| B: | 21 May 1527 |
| Valladolid, Castilla-Leon, Spain | |
| M: | 25 Jul 1554 |
| Winchester, Hampshire, England | |
| D: | 13 Sep 1598 |
| El Escorial, Madrid, Madrid, Spain | |
| (infant daughter) Tudor, (1st) | |
| D: | 31 Jan 1510 |
| King of England Lord of Ireland Henry Tudor, VIII | |
| B: | 28 Jun 1491 |
| Greenwich, Kent, England | |
| M: | 11 Jun 1509 |
| Greenwich, Kent, England | |
| D: | 28 Jan 1547 |
| London, England | |
|
| Queen of Castile and León, Queen consort of Aragon, Majorca, Naples, Sicily and Valencia Isabella van Castilië, Aragon | |
| B: | 22 Apr 1451 |
| Avila, Castilla-Leon, Spain | |
| D: | 26 Nov 1504 |
| Medina del Campo, Valladolid, Castilla-Leon, Spain | |
| King of Aragon, King of Sicily, King of Naples, and King of Valencia, Sardinia, and Navarre King Ferdinand de Aragón, II | |
| B: | 10 Mar 1452 |
| Sos, Huesca, Aragon, Spain | |
| M: | 19 Oct 1469 |
| Valladolid, Castilla-Leon, Spain | |
| D: | 23 Jan 1516 |
| Madrigalejo, CAceres, Extremadura, Spain | |